Study Suggests Significant NSAID Side Effects on Female Fertility
A new study has determined that the common non-steroidal anti-inflammatory drugs (NSAIDs) “Diclofenac”, “Naproxen” and “Etoricoxib” can decrease female fertility significantly. The effect was measured already after 10 days of intake1.
Worldwide, more than 30 million people take these drugs every day.
These non-steroidal anti-inflammatory drugs (NSAIDs) have previously shown to have a negative effect on fertility of animals2. In 2015, results of a human study with 39 women was presented by Dr. Sami Salman. 39 women with back pain received either
Diclofenac (100 mg per day), or
Naproxen (500 mg, twice a day), or
Etoricoxib (90 mg, once a day).
After 10 days of intake, progesteron levels of the women taking these pharmaceuticals were significantly lower. Only 6% of these women had their ovulation, while nearly all women taking a placebo (ineffective control substance) had regular ovulation and a normal progesteron level.
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By itself, the study is too small to attract international attention. Its findings, however, are alarming.
Women, who experience arthritis from an early age and who are keen on mothering a child conceive must be be even more careful with taking NSAIDs. They may have a significant impact on their reproductive system.
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